Director, Health Economics & Outcome Research

As a Director in Health Economics & Outcomes Research (HEOR) at BioNTech, you will play a pivotal role in shaping our value evidence strategies. Your work will directly impact clinical development decisions and support global launches, ensuring that our innovative therapies reach patients worldwide. Join a collaborative environment where your expertise will drive evidence generation across all stages of drug development, contributing to BioNTech’s mission of advancing global health.

In this position, you will be part of a dynamic team dedicated to staying at the forefront of HEOR methodologies. You’ll lead initiatives that inform regulatory-grade documents, reimbursement dossiers, and health technology assessments across diverse markets. Your contributions will be key to achieving BioNTech's strategic goals in clinical and commercial success.

Your Contribution:

• Develop and execute value evidence generation plans for systematic literature reviews (SLR), network meta-analyses (NMA), cost-effectiveness analyses (CEA), budget impact analyses (BIA), real-world evidence (RWE), and patient-reported outcomes (PROs).
• Conduct global epidemiology reviews to inform clinical trial site selection and recruitment strategies.
• Collaborate with medical experts and key opinion leaders through structured settings such as Delphi panels or advisory boards.
• Advise on FDA Guidance for PRO measures and Patient-Focused Drug Development (PFDD) in clinical programs.
• Oversee the creation of robust evidence synthesis plans to support global launches and reimbursement dossiers in key HTA and non-HTA markets.
• Train and support field teams with compliant HEOR tools, including pre-approval dossiers, launch models, and HCEI materials.

A Good Match:

• Advanced degree required (MS minimum; PhD/PharmD/MD preferred) in Public Health, Epidemiology, Outcomes Research, or related fields.
• Extensive experience with SLR methodology, NMA/ITC techniques, CEA/BIA models, and RWE research designs across US and international data sources.
• Proven track record in developing PROs, eCOA implementation, FDA COA meeting requests/briefing books, and negotiating regulatory PRO label claims.
• Expertise in health technology assessment guidelines (EU JCA implementation knowledge preferred).
• Strong communication skills with experience presenting HEOR research to payers or population health decision-makers.
• Demonstrated ability to mentor team members and foster professional growth within HEOR teams.

Expected Pay Range: $210,000/year to $240,000/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

Your Benefits:

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

…and more! More details to be shared.

Home to dozens of research institutions, biopharmaceutical companies, life science incubators, venture capital firms, and over 30 million square feet of laboratory space, Cambridge, Massachusetts has earned a reputation as the #1 life science cluster in the world. As part of the Greater Boston area, the city is often referred to as the "biotech supercluster" due to its high concentration of life sciences firms. This unique ecosystem is the result of a model partnership between academia and industry, fostering collaboration and innovation and driving the development of new therapies, medical devices, and diagnostics. As Cambridge’s thriving life sciences industry continues to evolve, the city remains a beacon of knowledge, innovation, and collaboration, poised to shape the future of science and technology.

Apply now - We look forward to your application!

Apply for our New Jersey, US location and simply send us your documents using our online form.

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.