Associate Principal Scientist, Continuous & Expression Technologies (Downstream) - Onsite

MSD Malaysia
Rahway, NJ

* As an impactful contributor, shape and realize innovation across biologics’ pipeline, strategy, and science* Advance best science incorporation into pipeline by collaborating with cross-functional teams, from Research & Manufacturing, in a fast-paced, multidisciplinary environment* Lead development of robust and scalable technologies for downstream processes for biologics* Identify areas for downstream process innovation/intensification and expand our technologies toolbox to address challenges at different stages of development (clinical, process characterization and commercialization)* Contribute to strategic initiatives; partner with senior leaders to set overall project strategy, and guide teams towards its execution* Conceptualize, plan, and execute projects with effective organizational, prioritization and problem-solving skills* Stay abreast of scientific and regulatory landscape; actively present (premier conferences), publish (peer-reviewed journals) and patent* Serve as Subject Matter Expert for intensified and/or continuous bioprocessing* Mentor and actively share expertise; guide career development; build strong, collaborative teams* Strong fundamental knowledge and subject matter expertise in downstream process development* Experience in continuous biomanufacturing and experimentation with integrated purification steps* Expertise in independently conducting and directing the design, execution, analysis, and documentation of all stages of downstream process development* Track record of accomplishments in downstream bioprocessing with a history of peer-reviewed publications and presentations* Adaptability and agility to prioritize and deliver complex objectives, often on tight timelines, in a rapidly changing environment* Experience and aptitude to lead, work, and collaborate in internal and external cross-functional, matrixed teams* Action-oriented, mindset for creativity; ability to take initiative, innovate, iterate, and problem-solve* Demonstrated commitment to coach and mentor staff to maximize talent development and utilization* Excellent interpersonal and communication skills**PREFERRED EXPERIENCE & SKILLS:** * Excellent interpersonal and communication skills* Experience with purification steps integrated with process-analytical technologies* High-throughput experimentation, automation, and process control* Experience with single-pass ultrafiltration and in-line diafiltration* Experience with high throughput experimentation using automation platforms such as TECAN* Experience using and/or programming process control systems such as DeltaV or PCS 7* Experience with multi-column chromatography systems (BioSMB, PCC, or similar)* Experience with statistical data analysis tools and design of experiments (JMP, Design Expert)* Experience with multivariate data analysis, machine learning, artificial intelligence* Experience with process modeling packages such as BioSolve Process, gPROMS, SuperPro Designer, or similar**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance #J-18808-Ljbffr

Posted 2026-01-15

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