Senior Systems Engineer II

At Insmed, every moment and every patient counts - and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you'll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person's contributions to meaningful progress. That commitment has earned us recognition as Science magazine's No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we're in. Are you?

About the Role:
As Senior Systems Engineer II, you will be a hands-on technical leader responsible for architecting, engineering, and operating enterprise-scale infrastructure across on-prem datacenters, virtual platforms, and cloud environments (AWS/GCP/Azure). You will manage the full lifecycle of compute, server provisioning, networking, storage, core services, monitoring, automation, security, and disaster recovery. You will also modernize legacy systems, drive automation-first operations, and deliver resilient, scalable, and secure infrastructure to support global business operations.

What You'll Do:

In this role, you'll have the opportunity to be a Senior Systems Engineer II. You'll also:

• Design, architect, and implement infrastructure solutions spanning on-premises datacenters, virtualized environments, and cloud platforms (AWS, GCP, Azure).
• Modernize compute, storage, and network services to improve reliability, performance, scalability, and security.
• Create high-quality architecture diagrams, technical specifications, and system design documentation.
• Lead end-to-end server provisioning and deprovisioning for Windows and Linux platforms.
• Install, configure, and maintain physical and virtual servers, ensuring consistent standards and optimized performance.
• Build automation for server builds, configuration, patching, drift detection, and lifecycle workflows using PowerShell, Python, Terraform, or Ansible.
• Integrate server provisioning and lifecycle tasks with ServiceNow automation and catalog workflows.
• Manage compute workloads across on-prem, virtual, and cloud environments, ensuring high performance and availability.
• Conduct capacity planning, performance tuning, and lifecycle governance across compute platforms.
• Support hybrid workload strategies aligned with business and application requirements.
• Manage hybrid storage environments (NetApp, SAN, NAS), replication, and disaster recovery configurations.
• Collaborate closely with Cybersecurity to reinforce hardening, vulnerability remediation, identity hygiene, and logging practices.
• Enhance monitoring and alerting across infrastructure platforms to ensure proactive detection and response.
• Contribute to disaster recovery planning, runbook creation, tabletop exercises, and failover testing.

Who You Are:

• Bachelor's degree in Computer Science, Information Technology, Engineering, or a related field required; Master's degree is a plus.
• 8+ years of progressive experience in Systems Engineering or Infrastructure Architecture, including at least 3-5 years working with compute platforms, and datacenter environments.
• Proven track record of driving change, innovation, automation, and process excellence in fast-paced, highly regulated environments.
• Strong hands-on experience across compute platforms, including Windows Server, Linux (Ubuntu/Red Hat), virtualization, storage, and networking. Knowledge of golden images.
• Experience managing compute in on-prem datacenters, virtual environments (VMware/Hyper-V), and cloud platforms (AWS, GCP, Azure).
• Advanced scripting and automation capabilities using PowerShell and Python, and experience with Infrastructure-as-Code tools such as Terraform or Ansible.
• Functional understanding of Directory Services (Active Directory, Azure AD/Entra ID, LDAP), as well as core Internet protocols including DNS, DHCP, SMTP, and SSL/TLS.
• Knowledge of firewall configuration, segmentation, and security policy implementation.
• Functional knowledge of backup and recovery platforms such as Druva, Commvault, Veeam, and DR planning/execution.
• Experience using ServiceNow or similar ITSM tools for ticketing, workflows, and lifecycle management.

Preferred

• Experience with multi-site infrastructure deployments and geographically distributed systems.
• Experience working in regulated environments such as GxP, CSV, NIST, ISO, or other compliance-driven frameworks.
• Prior experience in the pharmaceutical or biotech industry.
• Professional certifications such as MCSE, CCNA, AWS/GCP/Azure certifications, or related credentials are advantageous.

#LI-EG1

#onsite

Pay Range:
$113,000.00-143,500.00 Annual

Life at Insmed

At Insmed, you'll find a culture as human as our mission-intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

• Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
• Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
• 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
• Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
• Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.