Senior Director, Clinical Science - Oncology

As a Director/Senior Director of Clinical Science at BioNTech, you will be at the forefront of advancing groundbreaking therapies in oncology and immuno-oncology. Your leadership will shape innovative clinical development strategies, ensuring the safety and efficacy of investigational drugs while driving impactful contributions to BioNTech’s mission. Collaborating with dynamic cross-functional teams, you’ll play a pivotal role in executing global clinical studies and fostering continuous improvements in clinical data processes. This is your opportunity to lead with purpose, making a tangible difference in patients’ lives while working in a supportive and forward-thinking environment.

Your Contribution

• Design cutting-edge clinical trials in collaboration with Clinical Development Leads to evaluate investigational drugs’ safety and efficacy, including protocols, patient populations, and study endpoints.
• Ensure medical oversight of clinical trials, monitoring study progress, reviewing data, and managing adverse events in alignment with regulatory and ethical standards.
• Lead or contribute to creating essential documents such as study protocols, Investigator’s Brochures, regulatory submissions, and safety updates.
• Drive strategic alignment within Clinical Development by promoting best practices and enhancing cross-functional processes.
• Provide leadership for the Clinical Science team through talent acquisition, onboarding, training, performance management, and workforce planning.
• Collaborate across departments—clinical operations, biostatistics, regulatory affairs—to ensure successful execution of clinical programs.

A Good Match

• Bachelor’s degree in life sciences or healthcare; advanced degrees preferred.
• Extensive knowledge of Good Clinical Practice (GCP) guidelines and drug development processes across Phases 1–3; expertise in oncology/immuno-oncology highly desirable.
• Proven experience leading global clinical studies within pharmaceutical companies or CROs.
• Advanced skills in data management systems (e.g., EDC systems) with a focus on optimizing processes for continuous improvement.
• Strong ability to work effectively in matrixed environments while influencing stakeholders without direct authority.
• Exceptional adaptability under tight deadlines combined with high organizational skills to prioritize tasks effectively.
• Excellent verbal and written communication skills in English.
• BioNTech is committed to fostering innovation while maintaining a collaborative culture that empowers individuals to drive meaningful change. Join us as we shape the future of medicine together!

Expected US Pay Range: $260000 to $330000/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

Your Benefits:

BioNTech is committed to the wellbeing of our team members and offers a variety of benefits in support of our diverse employee base. We offer competitive remuneration packages which is determined by the specific role, location of employment and also the selected candidate’s qualifications and experience.

Note: The availability, eligibility and design of the listed benefits may vary depending on the location. The final requirements for the individual use of our benefits are based on the company's internal policies and applicable law.

How to apply:

Apply now by sending us your application documents including Curriculum Vitae, copy of ID, copies of degree certificates and professional certificates, motivation letter as well as your contact details via our online form.

Please note:

Only applications sent via our online form shall be considered. By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.

We are looking forward receiving your application.