Vice President, Product Development - CMC, Gene Therapy and Large Molecules

At Insmed, every moment and every patient counts - and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you'll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person's contributions to meaningful progress. That commitment has earned us recognition as Science magazine's No. 1 Top Employer for four consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we're in. Are you?

About the Role:
We are seeking a highly experienced and visionary Vice President, Product Development - CMC, Gene Therapy and Large Molecules, to help us expand what's possible for patients with serious diseases. Reporting to the SVP, Technical Operations, you will lead our gene therapy and large molecules pipeline from preclinical through clinical development and regulatory approvals. In this role you will be a key member of the Technical Operations leadership team and play a critical role in shaping strategy, building high-performing teams, and advancing innovative therapies to patients.

What You'll Do:

As the Vice President, Product Development - CMC, Gene Therapy and Large Molecules, you will define and execute the product development strategy for all gene therapy and large molecule programs, providing strategic direction and oversight throughout the development lifecycle and up through product approvals and launch.

In addition, you will oversee clinical development activities by working collaboratively with cross-functional leaders to ensure seamless execution of clinical trials and achieve regulatory milestones. Your role will be critical in coordinating efforts across multiple departments to advance our gene therapy and large molecule pipelines.

In this role you will also ensure that all Chemistry, Manufacturing, and Controls activities result in manufacturable, scalable, and compliant processes while maintaining supply chain readiness for both clinical and commercial needs. You will support global regulatory strategies by contributing to IND filings, BLA submissions, and pursuing orphan and rare disease designations that align with our therapeutic focus areas.

A key aspect of your role involves building and mentoring a high-performing product development team where you will foster a culture of innovation and accountability while developing talent within the organization.

Additionally, you will collaborate with external stakeholders including Contract Development and Manufacturing Organizations (CDMOs) and raw material suppliers to ensure reliable partnerships that support our development timelines and quality standards.

This position offers the opportunity to lead cutting-edge gene therapy development while building and inspiring a world-class team in the rapidly evolving field of genetic medicine.

Who You Are:

• PhD, or advanced degree in molecular biology, biotechnology, chemical engineering, or related field.
• 12-15+ years of progressive leadership experience in biopharma, with a strong track record in gene therapy or advanced biologics.
• Demonstrated success in advancing therapies through IND, clinical development and regulatory approvals.
• Deep understanding of vector biology (AAV, etc.), CMC requirements, and manufacturing for gene therapy.
• Strong leadership, communication, and organizational skills with proven ability to influence at all levels.
• Strategic thinker with the ability to operate effectively in a dynamic, fast-paced environment.

Where You'll Work

This can be a fully remote role because the selected candidate should be able to perform effectively from anywhere while staying connected to your Insmed team and community. Occasional travel for team meetings or events will be expected.

Alternatively, if you live within a drivable distance of Bridgewater, NJ, you'll have the option to work remotely most of the time, but with more in-person collaboration when it matters most.

Travel Requirements

This role requires occasional global travel (approximately 30%).

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Pay Range:
$329,000.00-398,326.00 Annual

Life at Insmed

At Insmed, you'll find a culture as human as our mission-intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

• Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
• Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
• 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
• Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
• Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.