Senior Principal Scientist, Clinical Research, Cardiovascular and Respiratory

Job Description

- The Senior Director (Senior Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed cardiovascular and respiratory medicines. With a focus on late-stage development, the Senior Director will manage the entire cycle of clinical development, including study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication.

Specifically, the Senior Director may be responsible for:

• Evaluating pre-clinical and translational work for the purpose of generating early clinical development plan and investigational new drug applications
  
• Developing clinical development strategies for investigational or marketed cardiovascular and respiratory drugs
  
• Planning clinical trials (design, operational plans, settings) based on these clinical development strategies
  
• Monitoring and managing the conduct of ongoing or new clinical trials for investigational or marketed cardiovascular and respiratory drugs
  
• Analyzing and summarizing clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication
  
• Participating in internal and joint internal/external research project teams relevant to the development of new compounds, and the further study of marketed compounds
  
• Support of business development assessments of external opportunities.
  

The Senior Director may:

• Supervise the activities of Clinical Scientists in the execution of clinical studies
  
• Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects
  
• Assist the leadership team in ensuring that appropriate corporate personnel are informed of the progress of studies of our Company's and competitors' drugs
  
• Obtain internal and external expert opinion on scientific questions relevant to areas of responsibility
  

The Senior Director is responsible for maintaining a strong scientific fund of knowledge by:

• Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies
  
• Identification of scientifically and operationally strong investigators who can assist in the development of our company's investigational and marketed drugs
  
• Establishing communications with prominent clinical investigators in his/her particular field of interest, particularly those who will be willing and able to assist in the evaluation of our company's drugs
  
• Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.
  

To accomplish these goals, the Senior Director may:

• Author detailed development documents, presentations, budgets, and position papers for internal and external audiences
  
• Facilitating collaborations with external researchers around the world
  
• Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.
  

Education

• M.D or M.D./Ph.D.
  

Required Experience and Skills

• Must have experience in industry or senior faculty in academia
  
• Minimum of 3 years of clinical medicine experience
  
• Minimum of 3-5 year of industry experience in drug development or biomedical research experience in academia
  
• Demonstrated record of scientific scholarship and achievement
  
• A proven track record in clinical medicine and background in biomedical research is essential
  
• Strong interpersonal skills, as well as the ability to function in a team environment, are essential
  

Preferred

• Board Certified or Eligible Cardiologist or Pulmonologist
  
• Prior specific experience in clinical research and prior publication.
  

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement•

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The salary range for this role is
$276,600.00 - $435,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: -We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: -We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully-
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.-

Employee Status:
Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:
Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):

Required Skills:
Cardiovascular Research, Cardiovascular Research, Clinical Development, Clinical Medicine, Clinical Research, Clinical Research Management, Clinical Studies, Clinical Testing, Clinical Trial Development, Clinical Trials, Communication, Data Analysis, Drug Development, Heart Disease, Intellectual Curiosity, Mentorship, Pharmaceutical Development, Pulmonary Arterial Hypertension, Pulmonary Disease Research, Pulmonary Disease Treatment, Pulmonary Disorders, Pulmonology, Regulatory Affairs Compliance, Regulatory Compliance, Scientific Consulting {+ 1 more}

-Preferred Skills:

Job Posting End Date:
09/19/2025
*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R361104