Director, Business Information Systems - Commercial

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Director, Business Information Systems - Commercial

Ivonescimab, also known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).
• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview of Role:

The Director of Business Information Systems will lead the strategic planning, implementation, and optimization of business-critical systems and data infrastructure across the Commercial organization. This role serves as a key liaison between business stakeholders and technology teams, ensuring seamless integration of CRM platforms, field execution tools, and data systems to drive operational excellence and informed decision-making.

Role and Responsibilities:

• Commercial Data Platforms & Environment Oversight: Establish and focus on strategy, execution, best practices, and innovative approaches in support of fundamental information procurement/exchange, data management environments, master data management, sales force automation, business intelligence, omnichannel, and advanced analytics environments.
• Business-to-Tech IT Liaison: Act as the primary bridge between business units and IT, translating business needs into technical requirements and ensuring alignment between technology solutions and strategic goals.
• Define and maintain business rules for data usage, quality, and governance to support operational and analytical needs.
• CRM / Applications / Portals Implementation & Oversight: Lead the end-to-end implementation, enhancement, and lifecycle management of CRM systems, business applications, and customer/partner portals to support commercial and operational objectives.
• Field Execution Applications Training: Develop and deliver training programs for field teams to ensure effective adoption and utilization of execution tools and applications.
• 360-Degree Data Integrations Coordination & Oversight: Oversee the integration of data across multiple systems to ensure a unified, accurate, and comprehensive view of customer and business data.
• Master Data Management (MDM) Oversight & Execution: Lead the development and enforcement of MDM strategies, ensuring data consistency, accuracy, and governance across all systems.
• BI Visualization Support: Partner with analytics teams to support the development and maintenance of business intelligence dashboards and data visualizations that drive insights and decision-making.
• Data Source Management for All Commercial Sources: Manage and optimize data pipelines and sources that support commercial operations, ensuring data integrity and availability.
• Data Governance / Clerking: Establish and enforce data governance policies, including data stewardship, compliance, and audit readiness.
• Omnichannel Data Integrations Partner: Collaborate with marketing, sales, and IT teams to integrate data across digital and traditional channels, enabling a seamless omnichannel customer experience.
• Advanced Analytics Data Sourcing: Identify, evaluate, and manage data sources required for advanced analytics initiatives, ensuring data is accessible, reliable, and aligned with business objectives
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor’s degree in Information Systems, Computer Science, Business Administration, or related field; Master’s degree preferred.
• Minimum of 10+ years of experience in business systems, IT, or data management roles required.
• Must have strong working experience with processing and understanding nuances of all data sets used in life science organizations including specialty pharmacy, specialty distributor, wholesaler, chargeback, medical claims, along with the other syndicated data available from third parties.
• Demonstrated experience supporting multiple functions across the entire spectrum of a Commercialization business departments including Field Sales, Marketing, Market Access/Trade, and Compliance.
• Proven experience implementing and managing CRM systems (e.g., Salesforce, Dynamics), business applications, and data integration platforms.
• Strong understanding of data governance, MDM, and business intelligence tools (e.g., Tableau, Power BI).
• Excellent communication and stakeholder management skills. Strong written and verbal communication is required. This includes communicating technical and non-technical related concepts to all levels of the organization, including executive level.
• Experience in a fast paced, commercial organization within the life sciences industry.
• Understanding data processing environments where third party aggregators or data HUBs are involved is required.

The pay range for this role is $197,500-$246,500 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at [email protected] to obtain prior written authorization before referring any candidates to Summit.