Associate Director, Sr. IT AI Program Manager

Insmed Incorporated
New Jersey
At Insmed, every moment and every patient counts - and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you'll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person's contributions to meaningful progress. That commitment has earned us recognition as Science magazine's No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we're in. Are you?

About the Role:
Insmed is making significant investments in educating its employees and expanding its AI capabilities across the organization. The realization of high-value outcomes from AI is a strategic imperative that will define our future growth.

We are seeking a Senior AI IT Program Manager to lead and organize Insmed's Artificial Intelligence portfolio within the IT Program Management Office. This role is actively engaged in the day-to-day workings of a complex AI portfolio, maintaining a strong, real-time pulse on AI initiatives across functions and lifecycle stages, while execution ownership remains with delivery leaders.

Reporting to the Senior Director of IT Program Management, this role focuses on portfolio orchestration and program maturity. You will provide structure, cadence, and guidance across a diverse set of AI initiatives, helping teams organize, sequence, and advance work in a consistent and disciplined way.

You will partner closely with delivery managers, IT business partners, and functional teams to translate strategic direction into an executable, well-governed AI portfolio. You will coordinate portfolio-level planning, organize mid-level cross-functional forums, and prepare inputs that enable effective governance and decision-making.

What You'll Do:

In the role of Sr IT AI Program Manager, you will:

  • Manage and coordinate a portfolio of AI and ML initiatives a ll Insmed functions e. g., Research , Development, Commercial, IT, and Enabling Functions.
  • Define , champion, and operationalize the AI program governance framework, including preparing and facilitating portfolio forums, review committees, and governance meetings.
  • Partner closely with IT Business Partners to support intake, evaluation, and prioritization of new AI use cases, ensuring portfolio alignment to maximize business value.
  • Provide leadership and coordination across a matrixed environment of IT Project Managers, business partners, and functions , reinforcing program discipline, quality standards, and cross-initiative alignment.
  • Implement robust portfolio-level risk management practices, translating technical challenges and potential blockers into business-relevant risks, impact assessments, and mitigation options.
  • Oversee and coordinate third-party vendors, external consulting partners, and outsourced service providers involved in AI initiatives, ensuring accountability and alignment with program objectives .
  • Maintain portfolio-level oversight of schedules, budgets, and resource planning, with the ability to quickly assess initiative health and intervene when alignment or stability is at risk.
  • L everage strong visual storytelling and presentation skills (expert proficiency in PowerPoint) to distill complex technical progress into clear, compelling narratives that support alignment and decision-making.
  • Provide clear, concise, and regular portfolio updates using project tracking tools (e.g., JIRA, Orchestra), and develop program scorecards tracking key performance indicators such as business impact, timeline, and budget variance.
Who You Are:

You have:

  • A Bachelor's degree in Computer Science , or a related field.
  • 10+ years of progressive experience in IT Project and Program Management, with at least 3+ years managing large, complex, multi-stream programs.
  • M inimum of 8 years' experience managing detailed project plans and leading teams in development and maintenance of planning activities.
  • In-depth working knowledge of Microsoft Project, or similar.
  • Highly proficient in Microsoft Office Powerpoint and other Office applications.
  • Effective verbal and written communication skills.
  • Experience in managing projects in a team environment, partnering with team leads to pr o vide good meeting management, pro-active and a self -starter.
Preferences :

  • Pr ofessional certification such as PMP (Project Management Professional), PgMP ( Program Management Professional), or similar methodology certifications (e.g., SAFe ).
  • D emonstrated experience managing Data, Analytics, or AI/Machine Learning specific programs.
  • Experience within the Life Sciences, Pharmaceutical, or Biotech industries .
Where You'll Work:
  • Hybrid (mix of work from home/corporate office 2+x per week)
Travel Requirements :

This role requires occasional [domestic/international/global] travel ( approximately 5- 10 %)

#LI-EG1

#hybrid

Pay Range:
$164,000.00-213,000.00 Annual

Life at Insmed

At Insmed, you'll find a culture as human as our mission-intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:
  • Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
  • Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
  • 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
  • Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
  • Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back
Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.
Posted 2026-02-14

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